STF-62247
Overview | |
Catalog # | bs-80220C |
Product Name | STF-62247 |
Specifications | |
Storage Buffer | powder |
Storage Condition | RT |
Target | |
Product Information | Molecular Weight:477.41 Formula:C15H13N3S Purity:>98% Solubility:Soluble in DMSO (up to 25 mg/ml). Chemical Name:N-(3-Methylphenyl)-4-(4-pyridinyl)-2-thiazolamine |
Description | Specifically induces autophagic cell death in VHL (von Hippel-Lindau)-deficient renal carcinoma cells both in vitro (IC50=625 nM) and in vivo. Renal cell carcinoma cell lines were radiosensitized by induction of autophagy following treatment with STF-62247. Cell permeable |