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MRL-24

Overview
Catalog # bs-80213C
Product Name MRL-24
Specifications
Storage Buffer powder
Storage Condition RT
Target
Product Information Molecular Weight:527.49

Formula:C28H24F3NO6

Purity:>98%

Solubility:Soluble in DMSO (up to 30 mg/ml)

Chemical Name:(S)-2-(3-((1-(4-Methoxybenzoyl)-2-methyl-5-(trifluoromethoxy)-1H-indol-3-yl)methyl)phenoxy)propanoic acid

Description Displays high affinity for PPARγ with excellent anti-diabetic activity in mice but poor PPARγ agonist activity in transcription and adipogenesis assays. Highly effective (30 nM) at blocking Cdk5-mediated phosphorylation of PPARγ. Cell permeable.