MRL-24
Overview | |
Catalog # | bs-80213C |
Product Name | MRL-24 |
Specifications | |
Storage Buffer | powder |
Storage Condition | RT |
Target | |
Product Information | Molecular Weight:527.49 Formula:C28H24F3NO6 Purity:>98% Solubility:Soluble in DMSO (up to 30 mg/ml) Chemical Name:(S)-2-(3-((1-(4-Methoxybenzoyl)-2-methyl-5-(trifluoromethoxy)-1H-indol-3-yl)methyl)phenoxy)propanoic acid |
Description | Displays high affinity for PPARγ with excellent anti-diabetic activity in mice but poor PPARγ agonist activity in transcription and adipogenesis assays. Highly effective (30 nM) at blocking Cdk5-mediated phosphorylation of PPARγ. Cell permeable. |