Nutlin-3

Overview
Catalog #	bs-80201C
Product Name	Nutlin-3
Specifications
Storage Buffer	powder
Storage Condition	-20°C
Target
Product Information	Molecular Weight:581.51 Formula:C30H30Cl2N4O4 Purity:>98% Solubility:Soluble in DMSO (up to 50 mg/ml), or in Ethanol (up to 50 mg/ml). Chemical Name:(±)-4-[4,5-Bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxy-phenyl)-4,5-dihydro-imidazole-1-carbonyl]-piperazin-2-one
Description	MDM2 antagonist; inhibits the MDM2-p53 interaction (IC50 = 0.09 μM) and activates p531. Displays antiproliferative activity and induces apoptosis in a variety of tumor cells2-4.