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Ilomastat (GM-6001)

Overview
Catalog # bs-80195C
Product Name Ilomastat (GM-6001)
Specifications
Storage Buffer powder
Storage Condition -20°C
Target
Product Information Molecular Weight:388.46

Formula:C20H28N4O4

Purity:>98%

Solubility:Soluble in DMSO (up to 10 mg/ml) or in Ethanol (up to 10 mg/ml).

Chemical Name:N-[(2R)-2-(Hydroxamidocarbonylmethyl)-4-methylpentanoyl]-L-tryptophan methylamide

Description Potent pan-specific inhibitor of matrix metalloproteinases (MMPs).1 Ki values have been reported for the following human MMPs: MMP-1, 0.4nM; MMP-2, 0.5nM; MMP-3, 27nM; MMP-7, 3.7nM; MMP-8, 0.1nM; MMP-9, 0.2nM; MMP-12, 3.6nM; MMP-14, 13.4nM; MMP-26, 0.36nM.2-4 Also inhibits MMP-10, MMP-13, MMP-15, MMP-17, MMP-20, MMP-21, TACE and ADAM19.