Garcinol

Overview
Catalog #	bs-80193C
Product Name	Garcinol
Specifications
Storage Buffer	powder
Storage Condition	-20°C
Target
Product Information	Molecular Weight:602.80 Formula:C38H50O6 Purity:>98% Solubility:Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml). Chemical Name:
Description	Garcinol is a HAT (histone acetyltransferase) inhibitor (p300 IC50=7µM and PCAF IC50=5µM) both in vitro and in vivo.1 It potentiates TRAIL-induced apoptosis of cancer cells. Garcinol, independent of the cell type, induces both of the TRAIL receptors, death receptor 4 (DR4) and DR5. Garcinol neither induces the receptors of normal cells nor sensitizes them to TRAIL.2