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NSC66811

Overview
Catalog # bs-80192C
Product Name NSC66811
Specifications
Storage Buffer powder
Storage Condition RT
Target
Product Information Molecular Weight:340.43

Formula:C23H20N2O

Purity:>98%

Solubility:Soluble in DMSO (up to 25 mg/ml).

Chemical Name:2-Methyl-7-[Phenyl(phenylamino)methyl]-8-quinolinol

Description A novel inhibitor of the MDM2-p53 interaction. Mimics three p53 residues involved in binding to MDM2. Binds to MDM2 with a Ki of 120 nM. Activates p53 in cancer cells. Cell permeable.