FH-535
| Overview | |
| Catalog # | bs-80188C |
| Product Name | FH-535 |
| Specifications | |
| Storage Buffer | powder |
| Storage Condition | -20°C |
| Target | |
| Product Information | Molecular Weight:361.21 Formula:C13H10Cl2N2O4S Purity:>98% Solubility:Soluble in DMSO (up to 25 mg/ml). Chemical Name:2,5-Dichloro-N-(2-methyl-4-nitrophenyl)benzenesulfonamide |
| Description | Suppresses Wnt/β-catenin signaling. It antagonizes PPARγ and PPARδ ligand-dependent activation which is mediated by inhibition of recruitment of the coactivators β-catenin and GRIP1 but not the corepressors NCoR and SMRT1. Inhibits the migration and growth of breast cancer cell lines2 as well as colon, lung and liver cell lines1. Useful tool for probing the involvement of Wnt signaling pathway3,4. |
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