Oxaprozin

Overview
Catalog #	bs-80083C
Product Name	Oxaprozin
Specifications
Storage Buffer	powder
Storage Condition	RT
Target
Product Information	Molecular Weight:293.32 Formula:C18H15NO3 Purity:>98% Solubility:Soluble in DMSO Chemical Name:4,5-Diphenyl-2-oxazolepropanoic acid
Description	Oxaprozin is a clinically useful non-steroidal anti-inflammatory drug.1 In addition to typical NSAID COX inhibition, Oxaprozin may also exert anti-inflammatory effects via inhibition of the Akt/IKK/NF-kappaβ pathway.2 The compound is capable of inhibiting both anandamide hydrolase in neurons (IC50= 85 µmol/l), with consequent potent analgesic activity, and NF-kappaB activation in inflammatory cells (IC50 = 50 µmol/l).3