Sulindac sulfone
| Overview | |
| Catalog # | bs-80080C |
| Product Name | Sulindac sulfone |
| Specifications | |
| Storage Buffer | powder |
| Storage Condition | RT |
| Target | |
| Product Information | Molecular Weight:372.41 Formula:C20H17FO4S Purity:>98% Solubility:Soluble in DMSO (up to 25 mg/ml). Chemical Name:(Z)-5-Fluoro-2-methyl-1-[p-(methylsulfonyl)benzylidene]indene-3-acetic acid |
| Description | Metabolite of the cyclooxygenase inhibitor sulindac that induces apoptosis via inhibition of type 5 phosphodiesterases.1 Sulindac sulfone does not inhibit cyclooxygenase at physiological concentrations but does inhibit K-ras-dependent cyclooxygenase-2 expression in colon cancer cells.2 |
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