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PKC-412

Overview
Catalog # bs-80070C
Product Name PKC-412
Specifications
Storage Buffer powder
Storage Condition RT
Target
Product Information Molecular Weight:570.65

Formula:C35H30N4O4

Purity:>98%

Solubility:Soluble in DMSO (up to 15 mg/ml) or in Ethanol (up to 2 mg/ml).

Chemical Name:4’-N-Benzoyl staurosporine

Description Broad spectrum kinase inhibitor. Inhibited kinases include, but are not limited to; PKA, PKC, S6 Kinase, KDR, PKC, Akt, EGFR, VEGFR, PDGFR, c-kit, and FLT-3. Acute myeloid leukemia related mutant forms of FLT-3 are also inhibited both in vitro and in vivo. PKC-412 has been demonstrated to induce apoptosis and shows broad antiproliferative activity in various tumor cell lines. Cell Permeable