PKC-412
Overview | |
Catalog # | bs-80070C |
Product Name | PKC-412 |
Specifications | |
Storage Buffer | powder |
Storage Condition | RT |
Target | |
Product Information | Molecular Weight:570.65 Formula:C35H30N4O4 Purity:>98% Solubility:Soluble in DMSO (up to 15 mg/ml) or in Ethanol (up to 2 mg/ml). Chemical Name:4’-N-Benzoyl staurosporine |
Description | Broad spectrum kinase inhibitor. Inhibited kinases include, but are not limited to; PKA, PKC, S6 Kinase, KDR, PKC, Akt, EGFR, VEGFR, PDGFR, c-kit, and FLT-3. Acute myeloid leukemia related mutant forms of FLT-3 are also inhibited both in vitro and in vivo. PKC-412 has been demonstrated to induce apoptosis and shows broad antiproliferative activity in various tumor cell lines. Cell Permeable |