Sivelestat

Overview
Catalog #	bs-80068C
Product Name	Sivelestat
Specifications
Storage Buffer	powder
Storage Condition	RT
Target
Product Information	Molecular Weight:456.45 Formula:C20H21N2O7 Purity:>98% Solubility:Soluble in DMSO (up to 20 mg/ml). Chemical Name:N-{2-[({4-[(2,2-Dimethylpropanoyl)oxy]phenyl}sulfonyl)amino]benzoyl}glycine sodium
Description	Potent and selective leukocyte elastase inhibitor, IC50 = 44 nM1. Displays no activity at a variety of other proteases. Inhibits NF-κB activation2 and LTB4-induced neutrophil migration in vitro3. Significantly attenuates ischemia-induced spinal cord injury, decreases serum cytokine levels and reduces acute inflammatory lung injury in vivo4.