EX-527
| Overview | |
| Catalog # | bs-80055C |
| Product Name | EX-527 |
| Specifications | |
| Storage Buffer | powder |
| Storage Condition | -20°C |
| Target | |
| Product Information | Molecular Weight:248.71 Formula:C13H13ClN2O Purity:>98% Solubility:Soluble in DMSO (up to 18 mg/ml) or in Ethanol (up to 10 mg/ml). Chemical Name:6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-xarboxamide (racemic) |
| Description | Selective SIRT1 inhibitor (IC50=98 nM). Does not inhibit other HDACs or SIRT family members. Increases p53 acetylation following DNA damage. Cell permeable. |
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