GW-5074
| Overview | |
| Catalog # | bs-80019C |
| Product Name | GW-5074 |
| Specifications | |
| Storage Buffer | powder |
| Storage Condition | -20°C |
| Target | |
| Product Information | Molecular Weight:520.95 Formula:C15H8Br2INO2 Purity:>98% Solubility:Soluble in DMSO (up to 50 mg/ml). Chemical Name:3-(3,5-Dibromo-4-hydroxybenzylidene)-5-iodo-1,3-dihydroindol-2-one |
| Description | Potent inhibitor of cRAF1 kinase (IC50 = 9 nM). Displays 100-fold selectivity for cRAF1 over CDK1, CDK2, c-src, ERK2, MEK, p38, Tie2, VEGFR2 and c-fm. Displays neuroprotective effects In vivo via a mechanism that is independent of MEK, ERK, and Akt signaling. Cell permeable. |
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