Overview |
bs-7750R-APC-Cy7 |
MKLP2 Polyclonal Antibody, APC-Cy7 Conjugated |
WB, IF(IHC-P), IF(IHC-F), IF(ICC) |
Human, Rat |
Mouse, Rabbit |
Specifications |
APC-Cy7 |
Rabbit |
KLH conjugated synthetic peptide derived from human KIF20A/MKLP2 |
353-450/890 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
10112 |
O95235 |
Cytoplasm |
MKLP2; RAB6KIFL; Kinesin-like protein KIF20A; GG10_2; Mitotic kinesin-like protein 2; Rab6-interacting kinesin-like protein; Rabkinesin-6; KIF20A |
Mitotic kinesin required for chromosome passenger complex (CPC)-mediated cytokinesis. Following phosphorylation by PLK1, involved in recruitment of PLK1 to the central spindle. Interacts with guanosine triphosphate (GTP)-bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end-directed motility. |
Application Dilution |
WB |
1:300-5000 |
IF(IHC-P) |
1:50-200 |
IF(IHC-F) |
1:50-200 |
IF(ICC) |
1:50-200 |