Amorolfine hydrochloride

Overview
Catalog #	bs-75863c-250-mg
Product Name	Amorolfine hydrochloride
Specifications
Storage Buffer	Powder
Storage Condition	Stable for 2 years after receipt when stored at RT.
Target
Product Information	CAS Number: 78613-38-4 Molecular formula: C21H35ON . HCl Molecular weight: 317.51 . 36.46 Purity: >98% (HPLC) Appearance: White powder. Solubility: Soluble in ethanol (20mg/ml), DMSO (5mg/ml) or PBS, pH7.2 (10mg/ml). InChiKey: XZKWIPVTHGWDCF-KUZYQSSXSA-N SMILES: C[C@H]1C[NH+](CC(C)CC2=CC=C(C(C)(C)CC)C=C2)C[C@@H](C)O1.[Cl-]
Description	Amorolfine (or amorolfin), is a morpholine antifungal drug that inhibits D14-sterol reductase and cholestenol D7-D8 isomerase, consequently depleting ergosterol and causes ignosterol to accumulate in the fungal cytoplasmic cell membranes in vivo. It acts primarily by inhibiting ergosterol biosynthesis, a component of fungal cell membrane, and possesses both fungistatic and fungicidal activity. Its spectrum of in vitro activity includes dermatophyte, dimorphic, dematiaceous and filamentous fungi and some yeasts.