Butyrolactone I

Overview
Catalog #	bs-75777c-200ug
Product Name	Butyrolactone I
Specifications
Storage Buffer	Solid
Storage Condition	Stable for 1 year after receipt when stored at +4°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Target
Product Information	CAS Number: 87414-49-1 Molecular formula: C24H24O7 Molecular weight: 424.5 Purity: >98% (HPLC, NMR) Appearance: White to off-white solid. Solubility: Soluble in DMSO, methanol, ethanol or acetone. InChiKey: NGOLMNWQNHWEKU-UHFFFAOYSA-N SMILES: COC(=O)[C@]1(CC2=CC=C(O)C(CC=C(C)C)=C2)OC(=O)C(O)=C1C1=CC=C(O)C=C1
Description	Cell permeable, potent and selective cyclin-dependent kinase CDK-1 (CDC2), -2 and -5 inhibitor [1-4, 9, 10]. Apoptosis inducer [6, 7, 9]. Antitumor agent [5, 9]. Inhibits cell cycle progression at the G1/S and G2/M transitions [8]. Shown to prevent the phosphorylation of retinoblastoma protein and H1 histone [2, 10]. Important probe for understanding the cellular roles of CDKs [4]. Inhibitor of alpha-glucosidases [12]. Maturation inhibitor of sheep oocytes [11].