Pseurotin A

Overview
Catalog #	bs-75653c-1mg
Product Name	Pseurotin A
Specifications
Storage Buffer	Powder
Storage Condition	Stable for 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C.
Target
Product Information	CAS Number: 58523-30-1 Molecular formula: C22H25NO8 Molecular weight: 431.4 Purity: >98% (HPLC) Appearance: White to off-white powder. Solubility: Soluble in methanol or ethyl acetate; poorly soluble in water. InChiKey: SLYDIPAXCVVRNY-UOWMTANKSA-N SMILES: CC1=C([C@@H](O)[C@@H](O)/C=C\CC)O[C@@]2([C@@H](O)[C@](OC)(C(C3=CC=CC=C3)=O)NC2=O)C1=O
Description	Antibiotic. Chitin synthase, monoamine oxidase and IgE production inhibitor. Cytotoxic. Shows nematicidal and antileishmanial activity. Antiproliferative against four different glioma cells. Downregulates the expression of tumour glycolytic enzymes pyruvate kinase M2 (PKM2) and lactate dehydrogenase 5 (LDH5) and upregulates the expression of pyruvate dehydrogenase beta (PDHB), adenosine triphosphate synthase beta (ATPB) and cytochrome C, important regulators for tricarboxylic acid cycle and oxidative phosphorylation. Inhibits activation of B-cells and differentiation into the plasma cells