Rosuvastatin . calcium salt

Overview
Catalog #	bs-75609c-10mg
Product Name	Rosuvastatin . calcium salt
Specifications
Storage Buffer	Solid
Storage Condition	Stable for 2 years after receipt when stored at -20°C.
Target
Product Information	CAS Number: 147098-20-2 Molecular formula: C22H27FN3O6S . 1/2Ca Molecular weight: 480.6 . 20.0 Purity: >98% (HPLC) Appearance: White to off-white solid. Solubility: Soluble in DMSO (20mg/ml) or DMF (20mg/ml). InChiKey: VGAZDTHGPVFCCO-YFRSHGDPSA-K SMILES: CN(S(C)(=O)=O)C1=NC(C2=CC=C(F)C=C2)=C(/C=C/[C@H](C[C@@H](O)CC([O-])=O)O)C(C(C)C)=N1.[Ca+2]
Description	Rosuvastatin is a potent competitive inhibitor of HMG-CoA reductase, the rate-limiting enzyme in the cholesterol biosynthetic pathway and the target of the statin class of cholesterol-lowering drugs. Rosuvastatin is antilipemic and is used to reduce plasma cholesterol levels and prevent cardiovascular disease. Formulations containing rosuvastatin reduce low-density lipoprotein (LDL) and C-reactive protein and increase high-density lipoprotein (HDL) in humans. Shown to have anti-inflammatory, antioxidant, antithrombotic and insulin sensitizing properties. Identified as a potential inhibitor of SARS-CoV-2, responsible for COVID-19.