AEBSF . hydrochloride

Overview
Catalog #	bs-75512c-50mg
Product Name	AEBSF . hydrochloride
Specifications
Storage Buffer	Solid
Storage Condition	Stable for 2 years after receipt when stored at -20°C.
Target
Product Information	CAS Number: 30827-99-7 Molecular formula: C8H10FNO2S . HCl Molecular weight: 203.2 . 36.5 Purity: >98% (HPLC) Appearance: White solid. Solubility: Soluble in water or 100% ethanol. InChiKey: WRDABNWSWOHGMS-UHFFFAOYSA-N SMILES: [Cl-].[NH3+]CCC1=CC=C(C=C1)S(F)(=O)=O
Description	Water soluble, irreversible serine protease (chymotrypsin, kallikrein, plasmin, thrombin and trypsin) inhibitor. Stable, non-toxic alternative to PMSF. Potent, selective inhibitor of Site-1-protease (S1P). Used to characterize the downstream result of SREBP inhibition and its influence on cholesterol regulation by selectively inhibiting S1P. NAD(P)H oxidase inhibitor. Inhibits activation of TGFbeta and activates JNK and p38 MAP kinases. beta-Secretase inhibitor. Shown to inhibit beta-amyloid peptide production and enhance APP (amyloid precursor protein) secretion in several cell lines at millimolar concentrations.