SAG . dihydrochloride (water soluble)
| Overview | |
| Catalog # | bs-75494c-1mg |
| Product Name | SAG . dihydrochloride (water soluble) |
| Specifications | |
| Storage Buffer | Solid |
| Storage Condition | Stable for 2 years after receipt when stored at -20°C. Store solutions at -20°C in the dark. |
| Target | |
| Product Information | CAS Number: 912545-86-9 and 364590-63-6 (both free base) Molecular formula: C28H28ClN3OS . 2HCl . 3H2O Molecular weight: 490.1 . 72.9 . 54.0 Purity: >98% (HPLC) Appearance: Light yellow solid. Solubility: Soluble in water or DMSO. InChiKey: IYXUQUYRWPGIQL-KOONDFAVSA-N SMILES: O.CNC1CCC(CC1)N(CC1=CC(=CC=C1)C1=CC=NC=C1)C(=O)C1=C(Cl)C2=CC=CC=C2S1 |
| Description | Cell permeable Sonic hedgehog (Shh) agonist. Cell permeable G-Protein-Coupled Receptor (GPCR) smoothened (Smo) agonist. Induces Sonic hedgehog (Shh) pathway activation and counteracts cyclopamine inhibition of Smo. Acts as an activator of Smo at low concentrations and as an inhibitor of Smo at very high concentrations. Potent activator of VEGF expression in vitro. |
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