Amlexanox

Overview
Catalog #	bs-75489c-10mg
Product Name	Amlexanox
Specifications
Storage Buffer	Solid
Storage Condition	Stable for 2 years after receipt when stored at -20°C.
Target
Product Information	CAS Number: 68302-57-8 Molecular formula: C16H14N2O4 Molecular weight: 298.3 Purity: >98% (HPLC) Appearance: White to off-white solid. Solubility: Soluble in DMSO (10mg/ml) or dimethylformamide (15mg/ml). Insoluble in water. InChiKey: SGRYPYWGNKJSDL-UHFFFAOYSA-N SMILES: CC(C)C1=CC2=C(OC3=C(C=C(C(O)=O)C(N)=N3)C2=O)C=C1
Description	Antiallergic [1,2]. Anti-inflammatory [2]. Antagonizes the angiogenic and mitogenic activity of FGF-1 through S100A13. Inhibits FGF-1 release [3, 5]. Binds to HSP90. Inhibits C-terminal chaperone activity [4]. Induces an increase in nonsense-containing mRNAs amount in treated cells, leading to the synthesis of functional full-length proteins in an efficient manner [6]. Selective inhibitor of TANK-binding Kinase 1 (TBK1) and IKKepsilon. Reversibly lowers weight and improves insulin sensitivity and reduces inflammation and attenuated hepatic steatosis in obese mices without affecting food intake [7].