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PLX4720

Overview
Catalog # bs-75487c-5mg
Product Name PLX4720
Specifications
Storage Buffer Solid
Storage Condition Stable for 2 years after receipt when stored at -20°C.
Target
Product Information CAS Number: 918505-84-7

Molecular formula: C17H14ClF2N3O3S

Molecular weight: 413.8

Purity: >99% (HPLC)

Appearance: Off-white solid.

Solubility: Soluble in DMSO or ethanol.

InChiKey: YZDJQTHVDDOVHR-UHFFFAOYSA-N

SMILES: CCCS(=O)(=O)NC1=CC=C(F)C(C(=O)C2=CNC3=NC=C(Cl)C=C23)=C1F
Description Potent and selective cell permeable B-Raf (V600E) and c-Raf-1 (Y340D/Y341D) inhibitor. Antitumor compound. ERK phosphorylation is potently inhibited exclusive in B-Raf(V600E)-bearing tumor cell lines.