Lac-Phe . acetate [N-Lactoyl-L-phenylalanine]

Overview
Catalog #	bs-75466c-10mg
Product Name	Lac-Phe . acetate [N-Lactoyl-L-phenylalanine]
Specifications
Storage Buffer	Powder
Storage Condition	Stable for 2 years after receipt when stored at -20°C.
Target
Product Information	CAS Number: 183241-73-8 Molecular formula: C12H15NO4 . C2H3O2 Molecular weight: 237.3 . 59.0 Purity: >95% (HPLC) Appearance: White to off-white powder. Solubility: Soluble in water. InChiKey: TXEKHKMVDUMVBF-GNAZCLTHSA-M SMILES: C[C@H](O)C(N[C@@H](CC1=CC=CC=C1)C(O)=O)=O.CC([O-2])=O
Description	Lac-Phe is an exercise-inducible metabolite, also called exerkine, that suppresses feeding and obesity. Lac-Phe is increased heavily with exercise in mammals and acts to reduce food intake and potentially decrease overall body weight and fat mass. In diet-induced obese mice, pharmacological administration of Lac-Phe led to decreased food intake, adiposity and body weight, as well as improved glucose homeostasis, while movement and energy expenditure were not affected. The biosynthesis of Lac-Phe from lactate and phenylalanine occurs in CNDP2+ cells, including macrophages, monocytes and other immune and epithelial cells.