Compound 112254 . hydrochloride (water soluble)
| Overview | |
| Catalog # | bs-75415c-10mg |
| Product Name | Compound 112254 . hydrochloride (water soluble) |
| Specifications | |
| Storage Buffer | Solid |
| Storage Condition | Stable for 2 years after receipt when stored at -20°C. |
| Target | |
| Product Information | CAS Number: 949745-75-9 (free base) Molecular formula: C26H35N3O3 . HCl . H2O Molecular weight: 437.6 . 36.5 . 18.0 Purity: >98% (HPLC, NMR) Appearance: White crystalline solid. Solubility: Highly soluble in DMSO. Soluble in 100% ethanol or methanol. Slightly soluble in water (1mg/ml). InChiKey: VLVXNJKVPFIWMW-UHFFFAOYSA-N SMILES: [Cl-].COC1=CC=C(C[NH+]2CCN(CC2)C(=O)CCNC(=O)C2=CC=C(C=C2)C(C)(C)C)C=C1 |
| Description | Adiponectin receptor (AdipoR) agonist. Binds to AdipoR1 and AdipoR2 less potent than AdipoRon (Prod. No. bs-75412C) [1, 2]. Activates 5'-adenosine monophosphate-activated protein kinase (AMPK) in cultured mammalian cells [1]. Improves diabetes, glucose and lipid metabolism and insulin sensitivity in cultured cells and in mice by AdipoR-dependent mechanisms [1]. |
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