MnTBAP chloride

Overview
Catalog #	bs-75407c-10mg
Product Name	MnTBAP chloride
Specifications
Storage Buffer	Powder
Storage Condition	Stable for 2 years after receipt when stored at -20°C.
Target
Product Information	CAS Number: 55266-18-7 Molecular formula: C48H28MnN4O8Cl Molecular weight: 879.2 Purity: >97% Appearance: Black crystalline powder. Solubility: Dissolve at 0.1M in aqueous base, then add buffer to lower pH to pH 7.0 or higher as needed. InChiKey: APHAGHGOUIMDLD-SAHKUQKESA-M SMILES: [Cl-].OC(=O)C1=CC=C(C=C1)C1=C2C=CC3=C(C4C=CC5=C(C6=CC=C7N6[Mn+3](N6C1C=CC6=C7C1=CC=C(C=C1)C(O)=O)(N45)N23)C1=CC=C(C=C1)C(O)=O)C1=CC=C(C=C1)C(O)=O
Description	Cell permeable superoxide dismutase (SOD) mimetic [1, 2]. Potent inhibitor of peroxynitrite-induced oxidative reactions (peroxynitrite scavenger), but not a scavenger of nitric oxide (NO) [3]. Neuronal apoptosis inhibitor [4]. Protects T cells from superoxide generation, caspase-dependent DNA loss and cell death [5]. Lipopolysaccharide-induced TNF-alpha production inhibitor, by prevention of intracellular ROS generation and subsequent inactivation of p38 MAPK and SAPK/JNK [6]. .