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Bisindolylmaleimide X . hydrochloride [Ro 31-8425]

Overview
Catalog # bs-75402c-1mg
Product Name Bisindolylmaleimide X . hydrochloride [Ro 31-8425]
Specifications
Storage Buffer Solid
Storage Condition Stable for 2 years after receipt when stored at -20°C. Store solutions at -20°C in the dark.
Target
Product Information CAS Number: 145317-11-9; 131848-97-0 (free base)

Molecular formula: C26H24N4O2 . HCl

Molecular weight: 424.5 . 36.5

Purity: >95% (HPLC)

Appearance: Red solid.

Solubility: Soluble in DMSO.

InChiKey: IMBOYWXMTUUYGZ-UHFFFAOYSA-N

SMILES: CC(C)(C=C)C12CC3N(C1NC1=C2C=CC=C1)C(=O)C1CC2(C(NC4=C2C=CC=C4)N1C3=O)C(C)(C)C=C
Description Selective protein kinase C (PKC) inhibitor [1-3]. Inhibits panel of protein kinases (e.g. GSK-3beta, CDK2) [3]. Inhibits superoxide generation in human neutrophils [1].