Pioglitazone

Overview
Catalog #	bs-75391c-1mg
Product Name	Pioglitazone
Specifications
Storage Buffer	Solid
Storage Condition	Stable for 2 years after receipt when stored at -20°C.
Target
Product Information	CAS Number: 111025-46-8 Molecular formula: C19H20N2O3S Molecular weight: 356.4 Purity: >98% (HPLC) Appearance: White to off-white solid. Solubility: Soluble in DMSO (2.5 mg/ml) or dimethylformamide (DMF) (2.5 mg/ml). InChiKey: HYAFETHFCAUJAY-UHFFFAOYSA-N SMILES: CCC1=CN=C(CCOC2=CC=C(CC3SC(=O)NC3=O)C=C2)C=C1
Description	Thiazolidinedione (TZD) reference compound [2, 3]. Selective PPARgamma agonist. Selectively activates PPARgamma-1 [1, 3]. Anti-diabetic [3-5], decreasing insulin resistance in adipose tissue. Is about one tenth as potent as rosiglitazone [1, 2]. Lipid metabolism modulator [6]. Estrogen synthesis inhibitor [7]. NF-kappaB inhibitor [8]. Neuroprotective [9].