AMI-1

Overview
Catalog #	bs-75372c-5mg
Product Name	AMI-1
Specifications
Storage Buffer	Solid
Storage Condition	Stable for 2 years after receipt when stored at -20°C.
Target
Product Information	CAS Number: 20324-87-2; 134-47-4 (free base) Molecular formula: C21H12N2O9S2Na4 Molecular weight: 592.4 Purity: >99% (NMR) Appearance: Brown solid. Solubility: Soluble in water, 100% ethanol or DMSO. InChiKey: OEJIOAHFKHHDAW-UHFFFAOYSA-J SMILES: [Na+].[Na+].[O-]C1=CC(=CC2=C1C=CC(NC(=O)NC1=CC3=C(C=C1)C([O-])=CC(=C3)S(=O)(=O)O[Na])=C2)S(=O)(=O)O[Na]
Description	Potent, cell permeable and specific protein arginine N-methyltransferase 1 (PRMT1) inhibitor (IC50 = 8.8 µM) [1]. Does not compete for the AdoMet (S-adenosyl-L-methionine; SAM) binding site [1]. Blocks peptide substrate binding [3]. HIV-1 RT polymerase inhibitor (IC50 = 5.0 µM) [2].