Ebselen
Overview | |
Catalog # | bs-75365c-1mg |
Product Name | Ebselen |
Specifications | |
Storage Buffer | Solid |
Storage Condition | Stable for 2 years after receipt when stored at -20°C. |
Target | |
Product Information | CAS Number: 60940-34-3 Molecular formula: C13H9NOSe Molecular weight: 274.2 Purity: >98% (HPLC) Appearance: White to off-white solid. Solubility: Soluble in DMSO (10mg/ml) or 100% ethanol (5mg/ml). InChiKey: DYEFUKCXAQOFHX-UHFFFAOYSA-N SMILES: O=C1N([Se]C2=C1C=CC=C2)C1=CC=CC=C1 |
Description | Glutathione peroxidase mimetic [1, 4]. Peroxynitrite scavenger [4]. Anti-inflammatory [1, 5-7] Antioxidant [2, 3, 5]. Protein kinase C (PKC), NADPH, lipoxygenase, COX, NOS, H+-ATPase and NADPH oxidase inhibitor [6-9]. Antifungal [9]. Review [10]. Potent IDO-1 inhibitor with Ki 94nM [11]. Inhibitor of HIV-1 capsid C-terminal domain dimerization. Shown to potentially inhibit the 33.8-kDa Main Protease (Mpro)/3C-like Protease of SARS-CoV-2, consequently inhibiting viral transcription and replication and possibly inhibiting spread of COVID-19. |