| Overview |
| bs-7534R-PE |
| PGC1 beta Polyclonal Antibody, PE Conjugated |
| WB |
| Human, Mouse, Rat, Dog, Cow, Pig, Rabbit, Guinea Pig |
| Specifications |
| PE |
| Rabbit |
| KLH conjugated synthetic peptide derived from human PGC1 beta |
| 901-1023/1023 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 133522 |
| Nucleus |
| PERC; peroxisome prolerative activated receptor, gamma, coactivator 1,; peroxisome prolerator-activated receptor gamma coactivator 1 beta; Peroxisome prolerator-activated receptor gamma coactivator 1-beta; peroxisome prolerator-activated receptor gamma, coactivator 1 beta; PGC-1beta; PGC-1-beta; PGC-1-related estrogen receptor alpha coactivator; PGC1; PPAR gamma coactivator-1beta; PPAR-gamma coactivator 1-beta; PPARGC-1-beta; PPARGC1; Ppargc1b; PRGC2_HUMAN. |
| Plays a role of stimulator of transcription factors and nuclear receptors activities. Activates transcritional activity of estrogen receptor alpha, nuclear respiratory factor 1 (NRF1) and glucocorticoid receptor in the presence of glucocorticoids. May play a role in constitutive non-adrenergic-mediated mitochondrial biogenesis as suggested by increased basal oxygen consumption and mitochondrial number when overexpressed. May be involved in fat oxidation and non-oxidative glucose metabolism and in the regulation of energy expenditure.Tissue specificity: Ubiquitous with higher expression in heart, brain and skeletal muscle. |
| Application Dilution |
| WB |
1:300-5000 |
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