FSL-1

Overview
Catalog #	bs-75295c-100ug
Product Name	FSL-1
Specifications
Storage Buffer	Powder
Storage Condition	Stable for 2 years after receipt when stored at -20°C.
Target
Product Information	CAS Number: 322455-70-9 Molecular formula: C84H140N14O18S Molecular weight: 1666.2 Purity: Absence of detectable protein or DNA contaminants with agonistic TLR activity. Appearance: Colorless powder. Solubility: Soluble in water (10mg/ml). Use a homogeniser or sonicator to prepare a homogenous solution. InChiKey: VJJLLNHELGKSNA-YWKNMTRCSA-N SMILES: [H]C(COC(=O)CCCCCCCCCCCCCCC)(CSC[C@]([H])(N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CN=CN1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=CC=C1)C(O)=O)OC(=O)CCCCCCCCCCCCCCC
Description	FSL-1 (Pam2CGDPKHPKSF) is a synthetic lipoprotein that represents the N-terminal part of the 44kDa lipoprotein LP44 of Mycoplasma salivarium [1]. FSL-1 is a mixture of R,R and R,S stereoisomers Stimulator of TLR2/TLR6 [2-11]. Inducer of TNF-alpha production in macrophages [4]. Upregulates proinflammatory cytokines [3, 4]. Activator of the proinflammatory transcription factor NF-kappaB [3].