Sipholenol A
Overview | |
Catalog # | bs-75261c-100ug |
Product Name | Sipholenol A |
Specifications | |
Storage Buffer | Powder |
Storage Condition | Stable for 2 years after receipt when stored at -20°C. |
Target | |
Product Information | CAS Number: 78518-73-7 Molecular formula: C30H52O4 Molecular weight: 476.7 Purity: >98% (HPLC) Appearance: White to off-white lyophilized powder. Solubility: Soluble in DMSO or 100% ethanol (25mg/ml). InChiKey: LVWWPNAIMBYRKG-KOHQYJKCSA-N SMILES: CC(O1)(C)[C@H](O)CC[C@@]2(C)[C@@]1([H])CC[C@@](O)(C)[C@@H]2CC[C@@H]3C(C)(C)[C@@](CC[C@@]4(C)O)([H])[C@@]4([H])CC=C3C |
Description | Efficient inhibitor of P-glycoprotein (Pgp, MDR-1) function through direct interactions. By inhibiting MDR-1, active compounds remain in the cytoplasm longer and allowing them to be more effective within the cell. Reversing agent for the treatment of multidrug resistance (MDR) in Pgp-overexpressing tumors. Potentiates the cytotoxicity of established Pgp substrates such as colchicine, vinblastine and paclitaxel. Antiproliferative and cytotoxic compound. Potent antifouling compound. |