Secalonic acid F
| Overview | |
| Catalog # | bs-75253c-1mg |
| Product Name | Secalonic acid F |
| Specifications | |
| Storage Buffer | Solid |
| Storage Condition | Stable for 2 years after receipt when stored at -20°C. |
| Target | |
| Product Information | CAS Number: 60687-07-2 Molecular formula: C32H30O14 Molecular weight: 638.6 Purity: >95% (HPLC) Appearance: Yellow solid. Solubility: Soluble in DMSO, ethanol or methanol. InChiKey: DRYDKQOPVBDZMQ-WVMRRKDFSA-N SMILES: OC1=C2[C@](OC3=CC=C(C4=C(O)C(C(C5=C(O)C[C@H](C)[C@H](O)[C@]5(C(OC)=O)O6)=O)=C6C=C4)C(O)=C3C2=O)(C(OC)=O)[C@H](O)[C@@H](C)C1 |
| Description | Mycotoxin. Common contaminant in corn and other grains. Hybrid dimer of Blennolide A and B. Cytotoxic anticancer compound. Reported to induce apoptosis by modulating RhoGDI 2 levels in HL60 cells. Protein tyrosine phosphatase 1B (PTP1B) inhibitor (IC50=9.6µM). PTP1B is thought to function as a negative regulator of insulin and leptin signal transduction and therefore being involved in type 2 diabetes and obesity pathology. Antimicrobial agent against Bacillus megaterium. Allelopathic agent. |
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