Streptozotocin

Overview
Catalog #	bs-75045c-50mg
Product Name	Streptozotocin
Specifications
Storage Buffer	Powder
Storage Condition	Stable for 2 years after receipt when stored at -20°C.
Target
Product Information	CAS Number: 18883-66-4 Molecular formula: C8H15N3O7 Molecular weight: 265.2 Purity: >98% (HPLC) \| >75% (alpha anomer) Appearance: Off-white to pale yellow powder. Solubility: Soluble in water or ethanol. InChiKey: ZSJLQEPLLKMAKR-GKHCUFPYSA-N SMILES: CN(N=O)C(=O)N[C@H]1[C@@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O
Description	Antibiotic [1]. Diabetogenic. Diabetes inducer. Induces diabetes mellitus in animal models through its toxic effects on pancreatic beta-cells [2, 5, 13, 14]. Mutagenic [3, 10]. Potent alkylating agent. Potent DNA methylating agent [4, 10]. Nitric oxide (NO) donor. Vasorelaxant [6]. Cytotoxic to cells that express GLUT2 glucose transporter [7]. O-GlcNAc-selective N-acetyl-beta-D-glucosaminidase (O-GlcNAcase) inhibitor [8]. Genotoxic. Induces DNA damage. Produces DNA strand breaks [9, 10]. Cell death inducer [15]. Antineoplastic. Anti-cancer agent used in chemotherapy [10, 11]. Induces cell cylce arrest at G2 [12].