Paclitaxel

Overview
Catalog #	bs-75044c-1mg
Product Name	Paclitaxel
Specifications
Storage Buffer	Powder
Storage Condition	Stable for 2 years after receipt when stored at -20°C.
Target
Product Information	CAS Number: 33069-62-4 Molecular formula: C47H51NO14 Molecular weight: 853.9 Purity: >99% (HPLC) Appearance: White powder. Solubility: Soluble in DMSO, ethanol or acetonitrile. InChiKey: RCINICONZNJXQF-MZXODVADSA-N SMILES: [H][C@@]12C[C@H](O)[C@@]3(C)C(=O)[C@H](OC(C)=O)C4=C(C)[C@H](C[C@@](O)([C@@H](OC(=O)C5=CC=CC=C5)[C@]3([H])[C@@]1(CO2)OC(C)=O)C4(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)C1=CC=CC=C1)C1=CC=CC=C1
Description	Anticancer compound [1, 11, 14]. Chemotherapeutic used in patients with cancer and advanced forms of Kaposi's sarcoma [11, 12]. Microtubule assembly stabilizer. Reversibly binds to polymerized tubulin [2, 3, 6, 13, 14]. Anti-mitotic. Mitotic spindle assembly, chromosome segregation and cell division inhibitor. Induces cell cycle arrest at the G2/M phase [4, 5, 10, 13]. Apoptosis inducer through aberrant activation of cyclin-dependent kinases (CKDs) and the c-Jun N-terminal kinase/stress activated protein kinase (JNK/SAPK) [7-9, 10]. Immunosuppressor. Immunostimulant [15]. Antiproliferative agent for the prevention of restenosis [16]. TRAIL sensitizer [17]