Latrunculin A

Overview
Catalog #	bs-75028c-100ug
Product Name	Latrunculin A
Specifications
Storage Buffer	Film
Storage Condition	Stable for 2 years after receipt when stored at -20°C. Store solutions at -20°C in the dark.
Target
Product Information	CAS Number: 76343-93-6 Molecular formula: C22H31NO5S Molecular weight: 421.6 Purity: >97% (HPLC) Appearance: Colorless viscous film Solubility: Soluble in DMSO (25mg/ml) or ethanol (25mg/ml). InChiKey: DDVBPZROPPMBLW-IZGXTMSKSA-N SMILES: O=C(SC1)N[C@]1([H])[C@](C2)(O)O[C@@H](C[C@H]2O3)CC[C@H](C)/C=C\C=C\CC/C(C)=C\C3=O
Description	Cell permeable marine toxin [1]. Disrupts microfilament-mediated processes [2]. Actin polymerization inhibitor in vitro and in vivo by the formation of a 1:1 complex with monomeric G-actin [1, 2, 3, 6]. Depolymerizes actin filaments (F-actin) [3]. Potent phagocytosis inhibitor [4]. Anticancer compound [7, 8]. Suppresses hypoxia-induced HIF-1 activation in tumor cells [7]. Inhibits tumor cell invasion [7]. Acts via a different mechanism than cytochalasins.