Anomalin A

Overview
Catalog #	bs-75012c-1mg
Product Name	Anomalin A
Specifications
Storage Buffer	Solid
Storage Condition	Stable for 2 years after receipt when stored at -20°C.
Target
Product Information	CAS Number: 548740-86-9 Molecular formula: C14H10O6 Molecular weight: 274.1 Purity: >97% (HPLC) Appearance: Yellowish solid. Solubility: Soluble in 100% ethanol or DMSO. InChiKey: YPBXGIBBOZOVPM-UHFFFAOYSA-N SMILES: [H]C1=C(O)C(O)=C(C)C2=C1OC1=C(C(O)=CC(O)=C1)C2=O
Description	Antiproliferative agent against selected cancer cell lines. Inhibits protein kinases ALK, ARK5, Aurora-B, AXL, FAK, IGF1-R, MET, PIM1, PLK1, PRK1, SRC, and VEGF-R2 with IC50 values between 0.3 and 75.7µM, most probably contributing to the antiproliferative activity. Shown to inhibit VEGF-A dependent endothelial cells sprouting with IC50 value of 1.8µM corresponding to its in vitro inhibitory activity against VEGF-R2 protein kinase (IC50=0.8µM). Lck (p56lck; lymphocyte specific tyrosine kinase) inhibitor. Antioxidant. DPPH radical scavenger.