| Overview |
| bs-7415R-Biotin |
| LSD2 / AOF1 Polyclonal Antibody, Biotin Conjugated |
| ELISA, IHC-P, IHC-F |
| Mouse, Rat |
| Human, Dog, Cow, Sheep, Pig, Horse, Rabbit |
| Specifications |
| Biotin |
| Rabbit |
| KLH conjugated synthetic peptide derived from human LSD2 / AOF1 |
| 51-150/822 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C for 12 months. |
| Target |
| 221656 |
| Q8NB78 |
| Nucleus |
| LSD2 / AOF1; KDM1B; amine oxidase (flavin containing) domain 1; amine oxidase, flavin containing 1; AOF1; bA204B7.3; C6orf193; dJ298J15.2; Flavin-containing amine oxidase domain-containing protein 1; FLJ33898; FLJ34109; FLJ43328; KDM1B; KDM1B_HUMAN; LSD2; lysine (K)-specific demethylase 1B; Lysine-specific demethylase 2; Lysine-specific histone demethylase 1B; Lysine-specific histone demethylase 2. |
| Histone demethylase that demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Required for de novo DNA methylation of a subset of imprinted genes during oogenesis. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and di-methylated 'Lys-4' of histone H3. Has no effect on tri-methylated 'Lys-4', mono-, di- or tri-methylated 'Lys-9', mono-, di- or tri-methylated 'Lys-27', mono-, di- or tri-methylated 'Lys-36' of histone H3, or on mono-, di- or tri-methylated 'Lys-20' of histone H4. |
| Application Dilution |
| ELISA |
1:500-1000 |
| IHC-P |
1:200-400 |
| IHC-F |
1:100-500 |
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