Takinib

Overview
Catalog #	bs-7222c-2mg-solid
Product Name	Takinib
Specifications
Storage Buffer	Powder
Storage Condition	Store in dry, dark place at -20C for 1 year.
Target
Product Information	Molecular Weight: 322.36 Formula: C18 H18 N4 O2 CAS Number: 1111556-37-6 InChi Key: UOZVVPXKJGOFIG-UHFFFAOYSA-N InChi: InChI=1S/C18H18N4O2/c1-2-10-22-15-9-4-3-8-14(15)20-18(22)21-17(24)13-7-5-6-12(11-13)16(19)23/h3-9,11H,2,10H2,1H3,(H2,19,23)(H,20,21,24) Smiles: CCCN1C(NC(=O)C2C=C(C=CC=2)C(N)=O)=NC2C=CC=CC1=2 Purity: 98.0 Solubility: Soluble in DMSO Appearance: Solid Power. Shelf Life: 1.0 years
Description	Takinib is a selective TAK1 inhibitor that induces apoptosis following TNF-α stimulation in cell models of rheumatoid arthritis and metastatic breast cancer. Takinib is an inhibitor of autophosphorylated and non-phosphorylated TAK1 that binds within the ATP-binding pocket and inhibits by slowing down the rate-limiting step of TAK1 activation.