SJF 1521, EGFR Degrader

Overview
Catalog #	bs-7179c-2mg-solid
Product Name	SJF 1521, EGFR Degrader
Specifications
Storage Buffer	Powder
Storage Condition	Store in dry, dark place at -20C for 1 year.
Target
Product Information	Molecular Weight: 1074.65 Formula: C57 H61 Cl F N7 O9 S CAS Number: 2230821-40-4 InChi Key: XZNORRXEBCTXPB-KHBXAZQSSA-N InChi: InChI=1S/C57H61ClFN7O9S/c1-36-52(76-35-63-36)40-10-8-37(9-11-40)30-60-55(69)49-29-44(67)31-66(49)56(70)53(57(2,3)4)65-51(68)33-73-23-22-71-20-21-72-24-25-74-45-16-12-39(13-17-45)41-14-18-48-46(27-41)54(62-34-61-48)64-43-15-19-50(47(58)28-43)75-32-38-6-5-7-42(59)26-38/h5-19,26-28,34-35,44,49,53,67H,20-25,29-33H2,1-4H3,(H,60,69)(H,65,68)(H,61,62,64)/t44-,49+,53-/m1/s1 Smiles: CC1N=CSC=1C1C=CC(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCCOC2C=CC(=CC=2)C2=CC3=C(NC4=CC(Cl)=C(C=C4)OCC4C=C(F)C=CC=4)N=CN=C3C=C2)C(C)(C)C)=CC=1 Purity: 98.0 Solubility: Soluble in DMSO Appearance: Solid Power. Shelf Life: 1.0 years
Description	SJF 1521 is a selective EGFR Degrader. It induces degradation of EGFR in OVCAR8 cells.