Bexarotene
Overview | |
Catalog # | bs-7095c-10mg-solid |
Product Name | Bexarotene |
Specifications | |
Storage Buffer | Powder |
Storage Condition | Store in dry, dark place at -20C for 1 year. |
Target | |
Product Information | Molecular Weight: 348.48 Formula: C24 H28 O2 CAS Number: 153559-49-0 InChi Key: NAVMQTYZDKMPEU-UHFFFAOYSA-N InChi: InChI=1S/C24H28O2/c1-15-13-20-21(24(5,6)12-11-23(20,3)4)14-19(15)16(2)17-7-9-18(10-8-17)22(25)26/h7-10,13-14H,2,11-12H2,1,3-6H3,(H,25,26) Smiles: CC1=CC2=C(C=C1C(=C)C1C=CC(=CC=1)C(O)=O)C(C)(C)CCC2(C)C Purity: 98.0 Solubility: Soluble in DMSO, not in water Appearance: Solid Power. Shelf Life: 1.0 years |
Description | Bexarotene, also known as LGD-1069, is a synthetic retinoic acid agent with potential antineoplastic, chemopreventive, teratogenic and embryotoxic properties. Bexarotene selectively binds to and activates retinoid X receptors (RXRs), thereby inducing changes in gene expression that lead to cell differentiation, decreased cell proliferation, apoptosis of some cancer cell types, and tumor regression. |