Dapivirine
Overview | |
Catalog # | bs-7066c-10mg-solid |
Product Name | Dapivirine |
Specifications | |
Storage Buffer | Powder |
Storage Condition | Store in dry, dark place at -20C for 1 year. |
Target | |
Product Information | Molecular Weight: 329.4 Formula: C20 H19 N5 CAS Number: 244767-67-7 InChi Key: ILAYIAGXTHKHNT-UHFFFAOYSA-N InChi: InChI=1S/C20H19N5/c1-13-10-14(2)19(15(3)11-13)24-18-8-9-22-20(25-18)23-17-6-4-16(12-21)5-7-17/h4-11H,1-3H3,(H2,22,23,24,25) Smiles: CC1C=C(C)C=C(C)C=1NC1C=CN=C(NC2C=CC(=CC=2)C#N)N=1 Purity: 98.0 Solubility: Soluble in DMSO, not in water Appearance: Solid Power. Shelf Life: 1.0 years |
Description | Dapivirine, also known as TMC120, is a non-nucleoside inhibitor for HIV reverse transcriptase with IC50 of 24 nM. The HIV-1 replication inhibitor dapivirine (DPV) is one of the most promising drug candidates being used in topical microbicide products for prevention of HIV-1 sexual transmission. |