Pexidartinib HCl

Overview
Catalog #	bs-7009c-10mg-solid
Product Name	Pexidartinib HCl
Specifications
Storage Buffer	Powder
Storage Condition	Store in dry, dark place at -20C for 1 year.
Target
Product Information	Molecular Weight: 454.28 Formula: C20 H16 Cl2 F3 N5 CAS Number: 2040295-03-0 InChi Key: CJLUYLRKLUYCEK-UHFFFAOYSA-N InChi: InChI=1S/C20H15ClF3N5.ClH/c21-15-6-16-14(10-28-19(16)29-11-15)5-12-2-4-18(26-7-12)27-9-13-1-3-17(25-8-13)20(22,23)24;/h1-4,6-8,10-11H,5,9H2,(H,26,27)(H,28,29);1H Smiles: Cl.FC(F)(F)C1=CC=C(CNC2C=CC(CC3=CNC4=NC=C(Cl)C=C34)=CN=2)C=N1 Purity: 98.0 Solubility: Soluble in DMSO Appearance: Solid Power. Shelf Life: 1.0 years
Description	Pexidartinib, also know as PLX-3397, is a CSF1R inhibitor with IC50 of 20 nM in development by Plexxikon for the treatment of tenosynovial giant cell tumors. It is in a phase 3 clinical trial for Pigmented Villonodular Synovitis (PVNS) or Giant Cell Tumor of the Tendon Sheath (GCT-TS).