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PD-123319 free base

Overview
Catalog # bs-6997c-10mg-solid
Product Name PD-123319 free base
Specifications
Storage Buffer Powder
Storage Condition Store in dry, dark place at -20C for 1 year.
Target
Product Information Molecular Weight: 508.61

Formula: C31 H32 N4 O3

CAS Number: 130663-39-7

InChi Key: YSTVFDAKLDMYCR-NDEPHWFRSA-N

InChi: InChI=1S/C31H32N4O3/c1-21-16-22(14-15-26(21)33(2)3)18-34-20-32-25-19-35(28(31(37)38)17-27(25)34)30(36)29(23-10-6-4-7-11-23)24-12-8-5-9-13-24/h4-16,20,28-29H,17-19H2,1-3H3,(H,37,38)/t28-/m0/s1

Smiles: CN(C)C1C=CC(CN2C=NC3CN([C@@H](CC2=3)C(O)=O)C(=O)C(C2C=CC=CC=2)C2C=CC=CC=2)=CC=1C

Purity: 98.0

Solubility: Soluble in DMSO

Appearance: Solid Power.

Shelf Life: 1.0 years
Description PD-123319 is a selective, nonpeptide AT2R antagonist (IC50 = 5.6 nM vs. 100 nM for AT1R). PD-123319 has been used to selectively examine the specific roles for AT1R and AT2R in hypertensive and other vascular research-related models..