LM11A-31 HCl
Overview | |
Catalog # | bs-6992c-10mg-solid |
Product Name | LM11A-31 HCl |
Specifications | |
Storage Buffer | Powder |
Storage Condition | Store in dry, dark place at -20C for 1 year. |
Target | |
Product Information | Molecular Weight: 316.27 Formula: C12 H27 Cl2 N3 O2 CAS Number: 1243259-19-9 InChi Key: LLIHJRRZJDEKLB-ULEGLUPFSA-N InChi: InChI=1S/C12H25N3O2.2ClH/c1-3-10(2)11(13)12(16)14-4-5-15-6-8-17-9-7-15;;/h10-11H,3-9,13H2,1-2H3,(H,14,16);2*1H/t10-,11-;;/m0../s1 Smiles: Cl.Cl.C[C@@H](CC)[C@H](N)C(=O)NCCN1CCOCC1 Purity: 98.0 Solubility: Soluble in DMSO Appearance: Solid Power. Shelf Life: 1.0 years |
Description | LM11A-31 is a small-molecule p75NTR modulator and proNGF antagonist, in preventing diabetes-induced BRB breakdown. Targeting p75NTR signalling using LM11A-31, an orally bioavailable receptor modulator, may offer an effective, safe and non-invasive therapeutic strategy for treating macular oedema, a major cause of blindness in diabetes. |