CHIR99021 trihydrochloride

Overview
Catalog #	bs-6933c-10mg-solid
Product Name	CHIR99021 trihydrochloride
Specifications
Storage Buffer	Powder
Storage Condition	Store in dry, dark place at -20C for 1 year.
Target
Product Information	Molecular Weight: 574.72 Formula: C22 H21 Cl5 N8 CAS Number: 1782235-14-6 InChi Key: DSFVSCNMMZRCIA-UHFFFAOYSA-N InChi: InChI=1S/C22H18Cl2N8.3ClH/c1-13-10-29-21(31-13)17-12-30-22(32-20(17)16-4-3-15(23)8-18(16)24)27-7-6-26-19-5-2-14(9-25)11-28-19;;;/h2-5,8,10-12H,6-7H2,1H3,(H,26,28)(H,29,31)(H,27,30,32);3*1H Smiles: Cl.Cl.Cl.CC1=CNC(=N1)C1=CN=C(NCCNC2=CC=C(C=N2)C#N)N=C1C1=CC=C(Cl)C=C1Cl Purity: 98.0 Solubility: Soluble in DMSO Appearance: Solid Power. Shelf Life: 1.0 years
Description	CHIR99021, CHIR-73911, also known as CT-99021, or CHIR-911, is an orally active and potent GSK3 inhibitor. CHIR-73911 exhibited GSK3 IC50 in the low nanomolar range and excellent selectivity. CHIR-73911 activates glycogen synthase in insulin receptorexpressing CHO-IR cells and primary rat hepatocytes.