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ML-347

Overview
Catalog # bs-6909c-10mg-solid
Product Name ML-347
Specifications
Storage Buffer Powder
Storage Condition Store in dry, dark place at -20C for 1 year.
Target
Product Information Molecular Weight: 352.39

Formula: C22 H16 N4 O

CAS Number: 1062368-49-3

InChi Key: FVRYPYDPKSZGNS-UHFFFAOYSA-N

InChi: InChI=1S/C22H16N4O/c1-27-17-9-7-15(8-10-17)16-12-24-22-20(13-25-26(22)14-16)18-4-2-6-21-19(18)5-3-11-23-21/h2-14H,1H3

Smiles: COC1C=CC(=CC=1)C1C=NC2=C(C=NN2C=1)C1C=CC=C2N=CC=CC=12

Purity: 98.0

Solubility: Soluble in DMSO, not in water

Appearance: Solid Power.

Shelf Life: 1.0 years
Description ML-347, also known as LDN193719, is a potent and selective bone morphogenetic protein receptor (BMP) inhibitor that inhibits ALK1 and ALK2 with IC50 values of 46 and 32 nM, respectively. ML347 shows >300-fold selectivity for ALK2.