LY3200882

Overview
Catalog #	bs-6898c-10mg-solid
Product Name	LY3200882
Specifications
Storage Buffer	Powder
Storage Condition	Store in dry, dark place at -20C for 1 year.
Target
Product Information	Molecular Weight: 435.52 Formula: C24 H29 N5 O3 CAS Number: 1898283-02-7 InChi Key: PNPFMWIDAKQFPY-UHFFFAOYSA-N InChi: InChI=1S/C24H29N5O3/c1-24(2,30)21-13-17(5-9-25-21)27-22-14-19(6-10-26-22)32-20-15-29(18-3-4-18)28-23(20)16-7-11-31-12-8-16/h5-6,9-10,13-16,18,30H,3-4,7-8,11-12H2,1-2H3,(H,25,26,27) Smiles: CC(C)(O)C1C=C(C=CN=1)NC1C=C(C=CN=1)OC1=CN(N=C1C1CCOCC1)C1CC1 Purity: 98.0 Solubility: Soluble in DMSO Appearance: Solid Power. Shelf Life: 1.0 years
Description	LY3200882 is an orally active TGFbeta inhibitor. LY3200882 targets transforming growth factor-beta (TGFb), with potential antineoplastic activity. Upon administration, LY3200882 specifically targets and binds to TGFb, which prevents both the binding of TGFb to its receptor TGFbR and TGFb-mediated signal transduction. This may lead to a reduction in TGFb-dependent proliferation of cancer cells.