Ripasudil HCl dihydrate

Overview
Catalog #	bs-6848c-10mg-solid
Product Name	Ripasudil HCl dihydrate
Specifications
Storage Buffer	Powder
Storage Condition	Store in dry, dark place at -20C for 1 year.
Target
Product Information	Molecular Weight: 395.88 Formula: C15 H23 Cl F N3 O4 S CAS Number: 887375-67-9 InChi Key: CMDJNMACGABCKQ-XVSRHIFFSA-N InChi: InChI=1S/C15H18FN3O2S.ClH.2H2O/c1-11-8-17-6-3-7-19(11)22(20,21)14-5-2-4-12-9-18-10-13(16)15(12)14;;;/h2,4-5,9-11,17H,3,6-8H2,1H3;1H;2*1H2/t11-;;;/m0.../s1 Smiles: O.O.Cl.C[C@H]1CNCCCN1S(=O)(=O)C1C=CC=C2C=NC=C(F)C2=1 Purity: 98.0 Solubility: Soluble in DMSO, not in water Appearance: Solid Power. Shelf Life: 1.0 years
Description	Ripasudil (K-115) is a specific inhibitor of ROCK, with IC50s of 19 and 51 nM for ROCK2 and ROCK1, respectively.