Verosudil

Overview
Catalog #	bs-6847c-10mg-solid
Product Name	Verosudil
Specifications
Storage Buffer	Powder
Storage Condition	Store in dry, dark place at -20C for 1 year.
Target
Product Information	Molecular Weight: 327.4 Formula: C17 H17 N3 O2 S CAS Number: 1414854-42-4 InChi Key: VDYRZXYYQMMFJW-UHFFFAOYSA-N InChi: InChI=1S/C17H17N3O2S/c1-20(2)15(12-6-8-23-10-12)17(22)19-13-3-4-14-11(9-13)5-7-18-16(14)21/h3-10,15H,1-2H3,(H,18,21)(H,19,22) Smiles: CN(C)C(C1=CSC=C1)C(=O)NC1C=C2C=CNC(=O)C2=CC=1 Purity: 98.0 Solubility: Soluble in DMSO, not in water Appearance: Solid Power. Shelf Life: 1.0 years
Description	Verosudil, also known as AR-12286, is a potent and selective Rho kinase inhibitor. AR-12286 was well tolerated and provided statistically significant reduction in IOP (intraocular pressure) in patients with XFS (exfoliation syndrome) and OHT (ocular hypertension) or XFG (exfoliative glaucoma). This drug may represent an additional therapeutic paradigm for the treatment of XFG.